KAMGRA ORAL JELLY
Kamagra CT 100 Chewabale Tabs
Sildenafil Citrate Chewable Tablets 100 mg
Each bilayered uncoated chewable tablet contains:
Sildenafil Citrate IP
Equivalent to Sildenafil 100 mg
KAMAGRA contains sildenafil that is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) in the corpus
cavernosum, where PDE5 is responsible for degradation of cGMP.
Sildenafil has a peripheral site of action on erections. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum but potently enhances the relaxant effect of NO on this tissue.
When the NO/cGMP pathway is activated, as occurs with sexual stimulation,Inhibition of PDE5 by sildenafil resuits in increased corpus caverrosurn
Levels cf cGMP. Therefore sexual stimulation is required in order for Sildenafil to produce its intended beneficial pharmacological effects.
INDICATIONS: Treatment of men with erectile dysfunction, which is the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance.
In order for KAMAGRA to be effective, sexual stimulation is recuired.
CONTRAINDICATIONS: Hypersensitivity to the active substance or to any of the encipients.
Consistent with its known effects on the nitric oxide/cyclic guanosine monophosphate (cGMP) pathway sildenafil was shown to potentate the hypotensive effects of nitrates, and its co-administration with nitric oxide donors (such as amyl nitrite) or nitrates in any form is therefore contraindicated.
Agents for the treatment of erectile dysfunction, including sildenafil, should not be used in men for whom sexual activity is inadvisable (e.g. patients with severe cardiovascular disorders such as unstable angina or severe cardiac failure).
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