KAMGRA ORAL JELLY
Fast Acting (Effervescent) Refreshing Orange Flavor
Each effervescent tablet contains:
Sildenafil Citrate equivalent to Sildenafil 100 mg
Color: Sunset yellow FCF
PHARMACOLOGICAL ACTION Sildenafil is a selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum. Sildenafil has no straight relaxant effect on isolated human corpus cavernosum but increase the relaxant effect of nitric oxide (NO) on this tissue. When the NO/cGMP pathway is activated. During sexual stimulation, inhibition of PDE5 by sildenafil results in increased corpus cavemosum levels of cGMP, producing smooth muscle relaxation in the corpus cavernosum allowing the inflow of blood.
Absorption: Sildenafil Citrate is quickly absorbed. Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state. The mean absolute oral bioavailability is 41% (range25-63%). The oral pharmacokinetics of Sildenafil Citrate is proportional over the recommended dose range (25-100 mg).
When Sildenafil Citrate is taken with a great fat meal, the rate of absorption is reduced with a mean delay in Tmax of 60 minutes and a mean reduction in Cmax of 29%.
© 2016 - Universal Health Care - All Rights Reserved - Hand Crafted By - .